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Ultram ER (Tramadol HCl Extended-Release) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxListULTRAM ER (tramadol hydrochloride) is a centrally acting synthetic analgesic in an extended-release formulation. The chemical name is ( ) cis-2-[(dimethylamino)methyl]- 1-(3-methoxyphenyl) cyclohexanol hydrochloride. Its structural formula is:The molecular weight of tramadol HCl is 299.8. It is a white, bitter, crystalline and odorless powder that is readily soluble in water and ethanol. ULTRAM ER tablets contain 100, 200 or 300 mg of tramadol HCl in an extended-release formulation. The tablets are white in color and contain the inactive ingredients ethylcellulose, dibutyl sebacate, polyvinyl pyrrolidone, sodium stearyl fumarate, colloidal silicon dioxide, and polyvinyl alcohol.Tramadol products in excessive doses, either alone or in combination with other
CNS depressants, including alcohol, are a major cause of drug-related deaths.
Fatalities within the first hour of overdosage are not uncommon. Tramadol should
not be taken in doses higher than those recommended by the physician. The judicious
prescribing of tramadol is essential to the safe use of this drug. With patients
who are depressed or suicidal, consideration should be given to the use of non-narcotic
analgesics. Patients should be cautioned about the concomitant use of tramadol
products and alcohol because of potentially serious CNS-additive effects of
these agents. Because of its added depressant effects, tramadol should be prescribed
with caution for those patients whose medical condition requires the concomitant
administration of sedatives, tranquilizers, muscle relaxants, antidepressants,
or other CNS-depressant drugs. Patients should be advised of the additive depressant
effects of these combinations.Ultram ER (tramadol) medical facts from Drugs.com
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Seizures (convulsions) have occurred in some people taking tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.
Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal. Overdose symptoms of a tramadol overdose may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, feeling light-headed, fainting, or coma. Tramadol may be habit-forming and should be used only by the person it was prescribed for. Tramadol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Tramadol can cause side effects that may impair your thinking or reactions.
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