TRAMADOL HCL SIDE EFFECTS - picture
tramadol hcl medication - picture
TRAMADOL HCL SIDE EFFECTS
The Side Effects of Tramadol HCL | eHow.com
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Tramadol hydrochloride (Hcl) is a prescription pain relief medication sold under the brand names Ultram and Ryzolt. It is available in regular tablets as well as extended release for people who need continuous pain medication for long periods of time. Many side effects are possible.
Tramadol Tablets Official FDA information, side effects and uses.
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Each tramadol hydrochloride tablet intended for oral administration contains 50 mg of tramadol hydrochloride. In addition, it also contains the following inactive ingredients: hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, pregelatinized starch, sodium starch glycolate, and titanium dioxide.Tramadol is extensively metabolized after oral administration by a number of pathways, including CYP2D6 and CYP3A4, as well as by conjugation of parent and metabolites. Approximately 30% of the dose is excreted in the urine as unchanged drug, whereas 60% of the dose is excreted as metabolites. The remainder is excreted either as unidentified or as unextractable metabolites. The major metabolic pathways appear to be N- and O-demethylation and glucuronidation or sulfation in the liver. One metabolite (O-desmethyltramadol, denoted M1) is pharmacologically active in animal models. Formation of M1 is dependent on CYP2D6 and as such is subject to inhibition, which may affect the therapeutic response (see PRECAUTIONS, Drug Interaction).
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Ultram (Tramadol Hcl) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxListULTRAM (tramadol hydrochloride) tablets is a centrally
acting analgesic. The chemical name for tramadol hydrochloride is ( )cis-2-[(dimethylamino)methyl]-1-(3methoxyphenyl)
cyclohexanol hydrochloride. Its structural formula is:The molecular weight of tramadol hydrochloride is 299.8.
Tramadol hydrochloride is a white, bitter, crystalline and odorless powder. It
is readily soluble in water and ethanol and has a pKa of 9.41. The
n-octanol/water log partition coefficient (logP) is 1.35 at pH 7. ULTRAM
tablets contain 50 mg of tramadol hydrochloride and are white in color.
Inactive ingredients in the tablet are pregelatinized corn starch, modified
starch (corn), hypromellose, lactose, magnesium stearate, microcrystalline
cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate,
titanium dioxide and carnauba wax.ULTRAM was administered to 550 patients during the
double-blind or open-label extension periods in U.S. studies of chronic
nonmalignant pain. Of these patients, 375 were 65 years old or older.
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